EORM Symposium 2023

From Concepts to Clinics: A New Era of Stem Cell Therapeutics

October 28-30, 2023
University of Vienna Biology Building (UBB) Djerassiplatz 1 1030 Vienna, Austria

ABOUT THE SYMPOSIUM

More than three decades of research on understanding, isolating and characterizing stem cells led to the development of this powerful technology. In recent years stem cell technology has been employed to generate specific cell types like cardiomyocytes, nephrons, neurons, oligodendrocytes and astrocytes etc for research and biotechnological applications. In addition, several clinical trials based on stem cells have started to treat patients suffering from various diseases. This EORM Symposium aims to connect researchers studying the stem cells for their application in research and the clinics. We envision a truly interdisciplinary meeting with presentations on various types of stem cells and their therapeutic applications.

About EORM Courses and Symposium

EORM Courses and Symposium are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).

Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.

5 October 2023

5 October 2023

Email

10 October 2023

Apply Now

Speakers


Professor Mark S. Brodie University of Chicago, USA

Professor Dr. Helmut KettenmannMax Delbruck Center Germany, Telethon Institute of Genetics and Medicine (TIGEM), IT

Professor Åsa EldénUniversity of Uppasala, Sweden

Professor B.Lynn Allen-HoffmannWisconsin University, USA

Professor Barbara AkumNew York University, USA

Professor Berger TrishPurdue University, USA

Professor Blatchford Richard University of California Davis, USA

Professor Carol A BagnellRutgers University, USA

Professor Clark ChenUniversity of Minnesota, USA

Professor Cowan ChadHarward University, USA

Professor Debbie CherneyCornell University, USA

Professor Dr. Michael GotthardtMax Delbruk Center Germany

Professor Gage Crump University of Southern California, USA

Professor Jonna FrasorUniversity of Chicago, USA

Professor Laura DolimpioUniversity of Birmingham, UK

Professor Marc N.WeinMassachusetts General Hospital, USA

Professor Marcus JarasLund University, Sweden

Professor Maria R. Baer University of Marryland, USA

Professor Michael Brainard University of California San Francisco, USA

Professor Mike BellisUniversity of Chester, UK

Professor Nigel PerkinsQueensland University, Australia

Professor Olle HintsTallinn University of Technology, Estonia

Professor Owen WilliamsUniversity college London, UK

Professor Paul MillsQueensland University, Australia

Professor Rachel HewettUniversity of Birmingham, UK

Professor Ryan AshleyNew Maxico State University, Maxico

Professor Sallie W.ChisholmMassachusetts Institute of Technology, USA

Professor Sergi MaicasUniversity of Valencia, Spain

Professor Theo PalmerStanford University, USA

Professor Victor AlbertUniversity of Buffalo, USA

Professor Victoria RidgwayUniversity of Chester, UK

Professor Yves BoisclairCornell University, USA

Programme

Session I: Evolution of bacteria defense: CRISPR-Cas and beyond

08:00-­09:00

Registration and poster set up

09:00­-09:15

Opening of the workshop by Organizers

09:15­-09:40

CRISPR vs. CRISPR

Francisco Mojica

09:40­-10:05

Coevolution between bacterial CRISPR-Cas systems and their bacteriophage

Stineke Van Houte

10:05­-10:30

CRISPR on the move: mechanistic insights into type V CRISPR-associated transposons

Irma Querques

10:30­-10:45

Selected talk from abstract

10:45-11:15

Coffee break

11:15-­11:40

Molecular innovation at the interface between CRISPR-Cas systems and transposable elements

Sam Sternberg

11:40-­12:05

Beyond CRISPR-Cas: Transposon-associated RNA-programmable TnpB nucleases

Manuela Baccarini

12:05­-12:20

Selected talk from the abstract

12:20­-12.35

Flash talks A

12.35-14.05

Lunch and poster set up

Session II: Novel CRISPR-Cas tools: More than double strand breaks

14:05­-14:30

Epigenetic editing

Angelo Lombardo

14:30-­14:55

Base Editing and Prime Editing: Precision Therapeutic Gene Correction in Cells, Animals, and Patients

David R. Liu (on line)

14:55-­15:20

TBA

Cecilia Cotta-Ramusino

15:20-15:35

Selected talk from abstract

15:35-­15:50

Selected talk from abstract

15:50-16:20

Coffee break

16:20-­16:45

Engineering CRISPR editors for heart cells

Julian Grünewald

16:45-­17:10

Expanding the CRISPR toolbox from natural reservoir

Anna Cereseto

17:10­-17:25

Selected talk from abstract

17:30-19.00

Poster Session A

Poster Session A

19:00-21:00

Welcome Cocktail

Session III: DNA repair

09:00-­09:25

Analysis of recombination hotspots in mouse germlines.

Maria Jasin

09:25­-09:50

Mechanistic insights to advance hematopoietic stem cell based gene therapies

Raffaella Di Micco

09:50-­10:05

Selected talk from abstract

10:05­-10:35

Coffee break

10:35­-11:00

Better genome editing by listening to the cells

Jacob E. Corn

11:00­-11:25

Harnessing DSB repair to promote efficient homology-dependent and -independent prime editing

Marcello Maresca

11:25­-11:40

Selected talk from abstract

11:40-­11:55

Selected talk from abstract

11.55-12.20

Flash Talks B

12.20-­14:00

Meet the speakers lunch

Session IV: Therapeutic development and clinical applications

14:00­-14:25

Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells.

Luigi Naldini

14:25-­14:50

Gene editing toolbox to correct hematopoietic cells from Fanconi anemia patients

Patrik Brundin

14:50-­15:15

Realizing the Promise of CRISPR Therapies: In Vivo Knockout and Insertion Programs

Laura Sepp-Lorenzino

15:15-­15:45

Coffee break

15:45­-16:10

In vivo prime editing of a metabolic liver disease in mice

Wenbin Deng

16:10­-16:35

First in human gene editing trial

Selim Corbacioglu

16:35-17:00

TBA

Annarita Miccio

17:00-­17:15

Selected talk from abstract

17:15­-17:30

Selected talk from abstract

Poster Session B

17.30-19:00

Poster Session B

19:00-20:30

Dinner on your own

Session V: CRISPR as tool in functional genomics and screenings

09:00-­09:25

Mapping the genetic landscape of DNA double-strand break repair

Britt Adamsom

09:25­-09:50

Identification and functional characterization in vitro and in vivo of ancestral CRISPR Cas systems

Lluis Montoliu

09:50-­10:05

Selected talk from abstract

10:05­-10:35

Coffee break

10:35­-11:00

New strategies for epigenetically silencing genes

Jonathan Weissman

11:00­-11:25

RNA-targeting CRISPR-Cas screenings to understand early development of vertebrates

Anna Halk

11:25-­11:50

Quantitative evaluation of chromosomal rearrangements in gene-edited human stem cells by CAST-Seq

Toni Cathomen

11:50-­12:05

Selected talk from abstract

Poster Session A and B

12:05-13:00

Poster Session A and B

13:00-14:00

Lunch

Session VI: Delivery

14:00-14:25

TBA

Daniel Siegwart

14:25-14:50

AAV and a split prime editor correcting disease-causing mutations

Erik Sontheimer

14:50-15:15

Therapeutic homology-independent targeted integration in retina and liver

Alberto Auricchio

15:15-15:30

Selected talk from abstract

16:30-18:30

Group visit Reales Alcazares and free time to visit downtown

19:00-22:00

Gala dinner at Muelle 21

Registration

  • Registration Deadline
  • 5 October 2023
  • Abstract Submission Deadline
  • 5 October 2023
  • Chosen Participants Will Be Notified By
  • Email
  • Payment Deadline
  • 10 October 2023
  • STUDENT/POSTDOCS EUR 450
  • ACADEMIC EUR 550
  • INDUSTRY EUR 950

a) Meeting is limited to 200 participants (including invited speakers).

b) Abstract submission and poster presentation are encouraged

c) Registration will be stopped on 5th October or earlier if all slots are covered.

d) Payment is required in order to validate this registration.

Registration includes:

  • Participation in the scientific event
  • Conference Materials
  • Meals (except dinner of the second night)

Excluding accommodation

Payment

The registration fee should be paid no later than October 10th

Selection criteria

Participants will be accepted by registration order.

Oral presentations and flash talks will be selected from submitted abstracts and a number of slots will be reserved for early career researchers. All selected participants will give their presentations in the form of posters.

Abstract guidelines

The abstract limit is 250 words.

Poster specifications

The poster size should be 1 m x 1.5 m (length x height) or A0 portrait. Specific time slots will be assigned for each participant to be present in person with his/her poster for direct scientific interaction.

Travel grants and registration fee waivers

Travel grants and registration fee waivers are available for participants.

Selection of awardees is handled directly by the organizers. EORM travel grants and registration fee waivers are allocated on the basis of the quality of the submitted abstract.

Applicants do not need to apply separately for these but should indicate on the registration form if they wish to be considered.

Additional travel grants are available for EMBC Associate Member States Chile, India, Singapore and Taiwan.

Special travel grants and registration fee waivers

A limited number of travel grants and registration fee waivers are availablefor scientists working in Croatia, Czech Republic, Estonia, Greece, Hungary, Italy, Lithuania, Luxembourg, Poland, Slovenia and Turkey. Grants are allocated on the basis of the quality of the submitted abstract.

A maximum of 700 Euros per participant are available to cover registration fees, travel, and accommodation (no additional subsistence costs can be covered). To apply, please indicate the itemized amount requested in the travel grants section of the registration form.

Child care grants

EORM Courses and Symposium offers grants to offset additional childcare costs incurred by participants or speakers when participating at any EORM Courses and Workshop funded meeting. Eligible costs include fees for a caregiver or child-care facility, travel costs for a caregiver, or travel costs for taking the child to the meeting etc. Please indicate on the registration form whether you would like to be considered for the grant. Please also describe how you intend to use the childcare grant and specify the sum that you will need.


Code of conduct

Anti-harassment and non-discrimination policy

At EORM, we believe that harassment and discriminatory behaviour are unacceptable in any setting. EORM's code of conduct is applicable for all participants of this EORM meeting and can be found here.

Contact

Organizer


Manuela Baccarini mbaccarini@EORM.eu Max Perutz Labs, Vienna, Austria

Co-Organizers


Patrik Brundin pbrundin@EORM.eu F. Hoffmann-La Roche, Basel, Switzerland

Revilla-i-Domingo rdomingo@EORM.eu University of Vienna, Austria

Anna Halk ahalk@EORM.eu Center for Advanced Therapy Medicinal Products (LU-ATMP), Lund University, Lund, Sweden

Wenbin Deng wdeng@EORM.eu Sun Yat Sen University, Guangzhou, China

 

Venue

University of Vienna
Biology Building (UBB) Djerassiplatz 1 1030
Vienna, Austria

Accommodation

Accommodations are not included in the registration fees and a list of suggested hotels will be provided

Transport

The journey time between Vienna International Airport and University of Vienna is around 37 min and covers a distance of around 24 km. This includes an average layover time of around 3 min. University of Vienna is accessible by buses or taxis from an international airport. Operated by Austrian Railways (ÖBB) and Wiener Linien, the Vienna International Airport to University of Vienna service departs from Flughafen Wien and arrives in University of Vienna. Typically 428 services run weekly, although weekend and holiday schedules can vary so check in advance.

About the Area

Change area location according to Austria